See a February 25, 2025, press release from LabCorp. Labcorp announce the clinical availability of a ctDNA based tumor gene profiling test, called Labcorp Plasma Complete (R). Here's their description, "Labcorp Plasma Complete detects genomic alterations in ctDNA across 521 genes. This includes single nucleotide variants (SNVs) and insertions/deletions (InDels), amplifications in 12 genes, translocations associated with 12 genes, and microsatellite instability (MSI) high status."
Find the full press release here:
The announcement is paired with a March 2025 publication in J Molec Dx (AMP), by Verner et al. It's titled, "Analytical Validation of the Labcorp Plasma Complete Test, a Cell-Free DNA Comprehensive Genomic Profiling Tool for Precision Oncology." Open Access; find it here:
https://www.jmdjournal.org/article/S1525-1578%2825%2900008-X/fulltext
Is it covered by MolDx?
Not sure. I couldn't find it on the MolDx DEX Registry, but Labcorp has >700 tests at dozens of lab locations and I may have missed something. Something called Labcorp Plasma Focus was listed, with the remark, "not covered." But that's not Plasma Complete, which my limited search effort did not find.
