Wednesday, October 26, 2022

Brief Blog: FORCE Supports New Book on Hereditary Cancer

FORCE, the organization "Facing Our Risk of Cancer Empowered," supported publication of a new book from Johns Hopkins University Press:  "Living with Hereditary Cancer Risk," Steligo and Friedman, editors.

The book was released in September 2022 and is available in paper, hardcover, and ebook from Amazon.

FORCE initially focused on individuals positive for BRCA mutations, but expanded its focus to multiple hereditary cancers and genes in 2020.

Find the FORCE webpage for the book's release here:

Find at Amazon here.

Clipping from FORCE web page below:

An explosion of discoveries since the 2012 publication of our book Confronting Hereditary Breast and Ovarian Cancer has improved what experts know about and how they approach hereditary cancers. Some of the most notable advances include:

  • new technology that lowered the cost of genetic testing and improved the ability to search for mutations in many genes in a single test.
  • the discovery of mutations in ATM, CHEK2, PALB2 and other genes that have been linked to hereditary breast, ovarian, pancreatic and/or prostate cancer risk. Although less research has been conducted on these genes, more information has become known as more people have had expanded panel testing. Most of these genes now have expert guidelines for risk management.
  • increased understanding of the genes linked to Lynch syndrome.
  • research on more effective, less invasive options for managing risk.
  • the development of targeted therapies to treat cancers in people with inherited mutations found with genetic testing or tumor mutations found with biomarker testing.

In recognition of these changes, FORCE expanded our mission in October 2020 from focusing solely on people with inherited BRCA mutations to also serve people with Lynch syndrome and those with a mutation in lesser-known genes including ATM, PALB2, BRIP1, CHEK2 and others that also raise the risk for one or more cancers.

With so many important changes in the world of hereditary cancer, we needed a new guide that reflects our commitment to providing accurate, up-to-date information and resources to the expanded high-risk community. Living with Hereditary Cancer Risk: What You and Your Family Need to Know, does just that.