For PLA Codes, find the AMA's 36-slide deck and FAQ at links provided.
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There are now over 600 AMA CPT PLA codes (proprietary laboratory analyses), and more are issued quarterly.
PLA codes are issued both for single-lab proprietary tests, and for distributed FDA approved or cleared tests.
Unfortunately, there is no master categorization of PLA codes: they are issued serially. So there's no index to which are genomic sequencing procedures, which are minimal residual disease, which are pharmacogenetic, and so on.
AMA CPT Speaker at Conference
On August 18, 2025, in Washington, hear two talks about lab codes to kick off the Next Generation Dx Summit, reimbursement track. On that Monday, Zach Hochstetler of AMA CPT Editorial & Regulatory Services, describes "Critical Updates to Lab CPT Codes." He's followed by Victoria Pratt (Indiana School of medicine and AMA PLA committee), on "PLA Codes and the CLFS Rate Setting Process."
Find agenda and registration here.
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There's a home page for all things PLA at the AMA CPT - here.
I was looking for some updates and ran across a detailed 36-page slide deck by AMA on PLA, as well as a detailed FAQ.
The 36-page deck is here. The FAQ is here.
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| sample slide |
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I noted in a July blog that, by inspecting PLA codes released over the last several quarters, they seemed to stop issuing digital-only lab PLA codes (blog here). For example, you could track some that were being applied-for but not finalized. I didn't see any direct confirmation of that in the AMA instructions.
